Venture capital giant Andreessen Horowitz has made one of the year’s most significant bets on the future of real estate and technology by spearheading a $250 million Series E investment in EliseAI, a PropTech company that has quickly established itself as a dominant force in artificial intelligence solutions for property management. The round, which pushed EliseAI’s valuation to roughly $2.2 billion, more than doubles the company’s worth from just a year ago and highlights the mounting role of AI in transforming industries beyond Silicon Valley.
Founded in 2017, EliseAI began with a simple mission: to reduce inefficiencies in multifamily housing operations. Over time, it has evolved into a sophisticated platform that leverages predictive analytics, conversational AI, and automated workflows to handle the full spectrum of leasing, maintenance, and tenant communications. Today, the company’s technology is used by over 600 property owners and operators, including some of the nation’s largest real estate firms such as Brookfield, AvalonBay Communities, Bozzuto, Equity Residential, and Invitation Homes. EliseAI’s platform automates tenant inquiries, handles lease audits, processes maintenance requests, and ensures transparency in fees—all of which reduce the workload on property managers while creating a smoother tenant experience.
Read Also: https://toplistings.com/navigating-real-estate-investment-trusts-reits-in-2025/
The $250 million investment marks a dramatic acceleration in the company’s trajectory. Just a year earlier, EliseAI closed a $75 million Series D round and had roughly 150 employees. Since then, the company has more than doubled its workforce, surpassing 300 employees, and earlier in 2025 announced that it had reached $100 million in annual recurring revenue. With this new funding, EliseAI plans to expand its offices in New York, San Francisco, Boston, and Chicago while also accelerating the development of AI solutions that go beyond property management into areas such as predictive site selection, maintenance forecasting, and secure digital transactions.
Andreessen Horowitz’s decision to lead the round signals the firm’s growing conviction that domain-specific AI platforms, often described as “vertical AI,” are uniquely positioned to reshape traditional industries. According to Alex Immerman, a growth partner at a16z, EliseAI already powers approximately 10 percent of the U.S. apartment market, with significant room to grow both domestically and internationally. Investors see this as the start of a much larger wave of AI adoption in real estate, where legacy processes have long been hampered by inefficiencies, fragmented data, and high costs.
Yet EliseAI’s ambitions extend beyond the property sector. The company has also developed applications tailored to healthcare, another industry burdened by administrative overhead. Its technology is being deployed to streamline scheduling, intake processes, prior authorizations, and other time-consuming tasks that can overwhelm clinics and front-office staff. By automating these functions, EliseAI claims it can cut overhead costs by as much as 25 percent while significantly reducing patient wait times and improving access to care. This dual focus on real estate and healthcare—two of the largest components of household spending in the United States—illustrates the scale of the company’s vision and the potential impact of its AI solutions.
The EliseAI investment also underscores a broader shift in capital flows into PropTech and AI-enabled platforms. Institutional investors have increasingly looked toward technology to bring greater transparency and efficiency to property transactions. In 2024 alone, more than £5.2 billion was invested in Build-to-Rent housing markets across Europe, with PropTech tools playing a growing role in shaping investment strategies. In the U.S., recent quarters have seen a surge in deals targeting automation, blockchain applications, and data-driven decision-making tools within real estate. EliseAI’s success demonstrates how quickly these innovations are moving from experimental to essential.
Observers note that EliseAI’s rise is emblematic of a new phase in PropTech’s evolution. Earlier waves of real estate technology were dominated by listing platforms and brokerage tools. Today, however, the focus is shifting toward integrated ecosystems where AI handles repetitive processes, predicts future needs, and creates measurable cost savings. For property managers, this means faster leasing cycles, fewer maintenance emergencies, and more reliable revenue streams. For tenants, it promises quicker responses, clearer communication, and a more seamless rental experience.
The endorsement by Andreessen Horowitz carries symbolic weight as well. Known for its early bets on transformative companies such as Airbnb, Coinbase, and Facebook, the firm’s backing often signals to the wider venture capital community that a startup has both the product and the market position to scale globally. Other participants in the round included Bessemer Venture Partners, Sapphire Ventures, and Navitas Capital, all of whom see EliseAI as a company positioned to define the future of property technology.
The implications of this deal stretch far beyond EliseAI’s own expansion. With AI adoption accelerating across nearly every sector of the economy, real estate and healthcare represent two of the most significant frontiers. Together, they account for nearly 40 percent of U.S. household spending. By tackling inefficiencies in these sectors, EliseAI is aiming to improve both the financial performance of large institutional investors and the day-to-day experiences of millions of consumers.
As the real estate market continues its uneven recovery from years of volatility, the adoption of technology platforms like EliseAI may help stabilize operations and unlock new value for both investors and residents. Whether it is forecasting maintenance before it becomes an emergency or ensuring a tenant’s request is answered in seconds rather than days, AI is rapidly becoming less of a luxury and more of a necessity. For Andreessen Horowitz, EliseAI represents not only a strong financial opportunity but also a chance to shape the next chapter of PropTech and enterprise AI adoption.